What is organic chemistry II useful for?

Department of Biology, Chemistry, Pharmacy

In the following you will find materials for the lecture, exercise sheets, dates, reading assignments and, if applicable, current information for the current semester, which will be published here parallel to the lecture.

General information about the OCI lecture can be found on the website of Dr. Thomas Lehmann.

Dates winter semester 2010/2011

Beginning October 18, 2010. Lecture Mon and Fri 10-12.

1st partial exam: Fri 10.12.2010

2nd partial exam: Mon 21.02.2011

Repeat exam: Thursday, March 24, 2011

The exam consists of two partial exams in which 100 points can be achieved each. At least 100 points must be achieved from both partial exams together. In the repeat exam, 200 points can be achieved, of which 100 points are required to pass.

Overall results OC I, Winter semester 2010/2011


The exercises will take place in the New Year from January 3rd, 2011. You can download the exercise sheet as a pdf below.

The exercise sheets are password protected.

The division into the exercise groups can be found here.

  • Group 1: Mon noon-2 p.m., room 34.17 / 18
  • Group 2: Tue 12 noon-2 p.m., room 23.03
  • Group 3: Wed 10 a.m.-12 p.m., room 24.16
  • Group 4: Wed noon-2 p.m., room 26.07
  • Group 5: Fri 8-10 a.m., room 23.03


Summary OC I - Part 1
Summary OC I - Part 2

List of the most important common names

Old exams


K. P. C. Vollhardt, N. E. Schore, Organic chemistry
4th edition 2005, Wiley-VCH, ISBN 3-527-31380-X
This book is a valuable addition to the lecture, which is why I will set a reading task every week with which you can prepare, review and deepen the lecture material. The Vollhardt goes far beyond the subject matter of the OC 1 lecture, much is dealt with in more detail in the OC 2. At the end of your bachelor's degree, however, you have to know and master what the Vollhardt says.

P. Y. Bruice, Organic chemistry
5th edition 2007, Pearson Studium, ISBN 978-3-8273-7190-4
This book also covers the material you need to get your bachelor's degree well. The structure is a little different from the lecture, which is perhaps not bad at all, because it allows you to see the lecture material in a different context. Many beautiful pictures, but very colorful for my personal taste. What I like a lot are the short biographies in the margin.

23rd edition 2009, Wiley-VCH, ISBN 3-527-32292-2
Not a comprehensive theoretical textbook, but a valuable helper in the laboratory. Regardless of the edition, it can be useful to you in the laboratory for a lifetime. You won't need it this semester, but it is highly recommended for the organic internship in the next semester.

Reading Assignments

Have prepared yourself well beforehand,
Paragraphos well rehearsed
So that you can see better afterwards,
That he says nothing but what is in the book; (...)
J. W. v. Goethe, Faust I.

The specified chapters relate to Vollhardt 4th edition. Various editions are available in the library, in which the numbering may differ. Please use the given headings to compare which chapter of your textbook corresponds to the given text.

  • 1st week (18.10. - 22.10.) Introduction, alkanes

    Vollhardt Chapter 1 "Structure and binding of organic molecules", Chapter 2 "Structure and reactivity: acids and bases, polar and non-polar molecules"

    The title of Chapter 2 is a bit misleading, it is about basic concepts and about alkanes.

  • 2nd week (25.10. - 29.10.) Alkanes, cycloalkanes

    Vollhardt Chapter 3 "Reactions of Alkanes", Chapter 4 "Cyclic Alkanes"

  • 3rd week (November 1st - November 5th) Alkenes

    Vollhardt Chapter 11 "Alkenes and ..." (without 11.4-11.6), Chapter 12 "Reactions of the alkenes"

  • 4th week (November 8th - November 12th) Alkenes, alkynes

    Vollhardt Chapter 13 "Alkynes" (without 13.3, 13.4, 13.8, 13.9), Chapter 14 "Delocalized π systems and ..." (without 14.9)

  • 5th week (November 15 - November 19) stereoisomerism and haloalkanes

    Vollhardt Chapter 5 "Stereoisomerism" (without 5.4), Chapter 6 "Properties and reactions of haloalkanes"

  • 6th week (November 22nd - November 26th) Reactions of the haloalkanes

    Vollhardt Chapter 7 "Further reactions of haloalkanes", Chapter 8 "The hydroxyl group: alcohols"

  • 7th week (November 29th - December 3rd) alcohols, ethers, amines

    Vollhardt Chapter 9 "Further reactions of alcohols and ...", Chapter 21.1-21.5 "Amines and their derivatives"

  • 9th week (13.12. - 17.12.) Aldehydes and ketones

    Vollhardt Chapter 17 "Aldehydes and Ketones: The Carbonyl Group" (excluding 17.3, 17.10-14)

    The chemistry of the carbonyl group is central to organic chemistry and biochemistry. You have to internalize and master chapters 17.5-17.9 in particular.

  • 10th week (03.01. - 07.01.) Aldehydes, ketones, carboxylic acids

    Vollhardt Chapter 18 "Enols and Enones", Chapter 19 "Carboxylic acids" (excluding 19.12)

    18.1-18.5 in particular are essential basics. Once you understand that (and why) carbonyl compounds are electrophilic and enolates are nucleophilic, all of the following reactions are just variations on one subject.

  • 11th week (January 10th - January 14th) Carboxylic acid derivatives, dicarbonyl compounds

    Vollhardt Chapter 20 "Derivatives of carboxylic acids and mass spectrometry", Chapter 23 "Dicarbonyl compounds and acyl anion equivalents" (excluding 23.4)

    We do not deal explicitly with mass spectrometry in this lecture. You can save 7/20, 8/20, and 9/20 for later. For 20.6 (amides), read also 21.5 and 21.6 (representation of amines) and compare the reactions. Acyl anion equivalents only appear in the OC II lecture, but it is of particular interest to biochemists.

  • 12th week (January 17th - January 21st) Sugar, amino acids

    Vollhardt Chapter 5.4 "Fischer projection", Chapter 24 "Carbohydrates" (excluding 24.10, 24.11), Chapters 26.1-26.4, 26.9 "Amino acids, peptides and proteins"

    Prepare 5.4 well: we will no longer discuss the Fischer projection in detail in the lecture.

  • 13th week (January 24th - January 28th) aromatics

    Vollhardt Chapter 15 "Benzene and Aromaticity"

    Compare with 12.5, 14.5-14.7.

  • 14th week (31.01. - 04.02.) Aromatics

    Vollhardt Chapter 16 "Electrophilic attack on benzene derivatives", Chapter 22 "Chemistry of the substituents on the benzene ring" (without 22.4, 22.7, 22.9, 22.10)

    Compare with 14.1-14.3.

  • 15th week (07.02. - 11.02.) Heterocycles, polymers

    Vollhardt Chapter 25 "Heterocycles", Chapter 12.14, 12.15 "Polymerization of Alkenes", Chapter 14.10 "Rubber"